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The Rounds Table
Medicine
internal medicine
randomized controlled trials
inpatient medicine
diabetes
cardiology
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Medicine

The Rounds Table

作者: Dr. John Fralick and Dr. Michael Fralick
最近更新: 7天前
<p>The Rounds Table is a free recurring medical podcast covering the latest and most important resea...

Recent Episodes

Episode 141 - Spironolactone in Patients on Maintenance Dialysis and Prophylactic Antibiotics for Upper GI Bleed in Cirrhosis

Episode 141 - Spironolactone in Patients on Maintenance Dialysis and Prophylactic Antibiotics for Upper GI Bleed in Cirrhosis

Send us a textWelcome back Rounds Table Listeners! We are back today with a Classic Rapid Fire episode. This week, Drs. Mike and John Fralick discuss two recent papers: the effects of spironolactone on heart failure and cardiovascular death in patients undergoing maintenance dialysis, and antibiotic prophylaxis in patients with cirrhosis and upper gastrointestinal bleeding. Two papers, here we go!Spironolactone versus placebo in patients undergoing maintenance dialysis (ACHIEVE): an international, parallel-group, randomised controlled trial (0:00 – 7:19)Prophylactic Antibiotics for Upper Gastrointestinal Bleeding in Patients With Cirrhosis: A Systematic Review and Bayesian Meta-Analysis (7:20 – 15:08)And for the Good Stuff (15:09 – 17:51):The $500m slugger who helped Canada get to the World SeriesClinical practice guidelines one-pagers coming soon to Trial Files: https://trialfiles.substack.com/Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods

2个月前
1071
TBT - Airway Management in Acute Poisoning and the PALACE Trial

TBT - Airway Management in Acute Poisoning and the PALACE Trial

Send us a textWelcome back Rounds Table Listeners! In this throwback episode (initial release 14 Mar 2024), Dr. Mike Fralick and special guest, Dr. Laiya Carayannopoulos from the Intern at Work Podcast, discuss two papers: one exploring the role of non-invasive ventilation in comatose patients after acute poisoning, and and one on the use of the PEN-FAST Score in the point-of-care risk assessment of penicillin allergy. Two papers, here we go!Effect of Noninvasive Airway Management of Comatose Patients With Acute Poisoning (0:00 – 16:25).Efficacy of a Clinical Decision Rule to Enable Direct Oral Challenge in Patients With Low-Risk Penicillin Allergy (16:26 – 24:17).And for the Good Stuff:Celebrating Research Success! (24:18 – 25:14).Non-inferiority results: everything you need know in 5 minutes! and Is Noninferior Not Inferior? (25:15 – 26:48).Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods

2个月前
1608
Episode 140 - Spironolactone vs. Amiloride for Resistant Hypertension

Episode 140 - Spironolactone vs. Amiloride for Resistant Hypertension

Send us a textWelcome back Rounds Table Listeners! Today we have a solo episode with Dr. Mike Fralick. This week, he discusses a recent trial examining whether amiloride is noninferior to spironolactone in reducing systolic blood pressure in patients with resistant hypertension. Here we go!Spironolactone vs Amiloride for Resistant Hypertension: A Randomized Clinical Trial (0:00 – 8:10).Run-in studies:Application and impact of run-in studiesApplication and Impact of Run-In Studies for the Evaluation of Statin Efficacy and SafetyThe Good Stuff (8:11 - 9:14):Trial Files: https://trialfiles.substack.com/Heme Onc Trial Files: https://hemeonctrialfiles.substack.com/Allergy & Immunology Trial Files: https://allergyimmtrialfiles.substack.com/Critical Care Trial Files: https://criticalcaretrialfiles.substack.com/Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods

2个月前
554
Episode 136 - Aspirin in Patients with Chronic Coronary Syndrome receiving Oral Anticoagulation

Episode 136 - Aspirin in Patients with Chronic Coronary Syndrome receiving Oral Anticoagulation

Send us a textWelcome back Rounds Table Listeners! Today we have a solo episode with Dr. Mike Fralick. This week, he discusses a recently published trial looking at aspirin in patients with chronic coronary syndrome receiving oral anticoagulation. Here we go!Aspirin in Patients with Chronic Coronary Syndrome Receiving Oral Anticoagulation (0:00 – 9:43).Throwback to EPIC-CAD: The Rounds Table Episode 94: Top Papers from the 2024 European Society of Cardiology Congress The Good Stuff:Trial Files is a free monthly newsletter on practice-changing trials, delivered straight to your inbox (https://trialfiles.substack.com/).Guidelines summaries coming to Trial Files soon!Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods

3个月前
583
Episode 135 - Top Papers from the 2025 European Society of Cardiology (ESC) Congress

Episode 135 - Top Papers from the 2025 European Society of Cardiology (ESC) Congress

Send us a textWelcome back Rounds Table Listeners! We are back today with a special Rapid Fire Podcast. This week, Drs. Mike and John Fralick discuss some of the top papers from the 2025 European Society of Cardiology (ESC) Congress. Hot off the presses, here we go!Increasing the Potassium Level in Patients at High Risk for Ventricular Arrhythmias (0:00 - 5:23)Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction (5:24 - 10:23)RSV Prefusion F Vaccine for Prevention of Hospitalization in Older Adults (10:24 - 16:09)Apixaban for Extended Treatment of Provoked Venous Thromboembolism (16:10 - 20:55)The Good Stuff (20:56 - 22:53):Thrombo Trial Files (https://thrombotrialfiles.substack.com/)John Candy: I Like Me at the Toronto International Film Festival The I'm Pharmacy podcast is now live on www.medicinepods.com Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods

3个月前
1373
Episode 131 - Zoledronate for Fracture Prevention and Semaglutide in Type 1 Diabetes and Obesity

Episode 131 - Zoledronate for Fracture Prevention and Semaglutide in Type 1 Diabetes and Obesity

Send us a textWelcome back Rounds Table Listeners! We are back today with a Classic Rapid Fire episode. This week, Drs. Mike and John Fralick discuss two recent papers: the effects of infrequent zoledronate administration on vertebral fracture prevention in early postmenopausal women, and the efficacy and safety of semaglutide in adults with type 1 diabetes and obesity. Two papers, here we go!Fracture Prevention with Infrequent Zoledronate in Women 50 to 60 Years of Age (0:00 – 10:24)Semaglutide in Adults with Type 1 Diabetes and Obesity (10:25 – 17:48)And for the Good Stuff (17:49 – 19:46):Canadian tennis player Victoria Mboko wins the Canadian Open!The I'm Pharmacy podcast— coming soon to www.medicinepods.com.Thank you to our sponsor, FIGS scrubs. Rounds Table listeners can save 20% on their next purchase with code FIGSCA at https://www.wearfigs.com/.Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods

4个月前
1186
Episode 130 - Hypotension-Avoidance vs Hypertension-Avoidance and Albuterol–Budesonide in Mild Asthma

Episode 130 - Hypotension-Avoidance vs Hypertension-Avoidance and Albuterol–Budesonide in Mild Asthma

Send us a textWelcome back Rounds Table Listeners! We are back today with a Classic Rapid Fire episode. This week, Drs. Mike and John Fralick discuss two recent papers: the effects of perioperative hypotension-avoidance versus hypertension-avoidancestrategies on delirium and 1-year cognitive decline after noncardiac surgery, and the effect of as-needed albuterol–budesonide on risk of severe asthma exacerbation among patients with moderate-to-severe asthma. Two papers, here we go!Effects of a Hypotension-Avoidance Versus a Hypertension-Avoidance Strategy on Neurocognitive Outcomes After Noncardiac Surgery (0:00 – 11:25)As-Needed Albuterol–Budesonide in Mild Asthma (11:26 – 21:12)And for the Good Stuff (21:13 – 23:17):Shout out to all the emergency medicine physicians!If you are interested in checking out the alpha version of the chatbot for One-Pagers for the Wards, reach out to Mike at fralickmpf@gmail.com.Thank you to our sponsor, FIGS scrubs. Rounds Table listeners can save 20% on their next purchase with code FIGSCA at https://www.wearfigs.com/.Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods

4个月前
1397
TBT - The Top 5 Papers of 2024

TBT - The Top 5 Papers of 2024

Send us a textWelcome back Rounds Table Listeners! In this throwback episode, Drs. Mike and John Fralick chat about five important research studies published in 2024:Finerenone in Heart Failure with Mildly Reduced or Preserved Ejection Fraction (FINEARTS-HF) (0:00 – 4:09)Tirzepatide for the Treatment of Obstructive Sleep Apnea and Obesity (SURMOUNT-OSA) (4:10 – 9:28)Effects of Semaglutide on Chronic Kidney Disease in Patients with Type 2 Diabetes (FLOW) (9:29 – 14:23)Tirzepatide for Metabolic-Dysfunction Associated Steatohepatitis with Liver Fibrosis (SYNERGY-NASH) (14:24 – 20:28)Antibiotic Treatment for 7 versus 14 Days in Patients with Bloodstream Infections (BALANCE) (20:29 – 23:59)And for the Good Stuff:Toronto Star Santa Claus Fund, Calgary Food Bank, Epilepsy Canada (24:00 - 25:23)Calling keen trainees!Trainees, med students, residents: The Rounds Table and Trial Files (https://trialfiles.substack.com/) are looking for keen individuals to support our efforts.Reach out to fralickmpf@gmail.com if you are interested in getting involved. Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods

5个月前
1523
Episode 128 - Finerenone with SGLT2 inhibitors for CKD and Type 2 Diabetes

Episode 128 - Finerenone with SGLT2 inhibitors for CKD and Type 2 Diabetes

Send us a textWelcome back Rounds Table Listeners! Today we have a solo episode with Dr. Mike Fralick. This week, he discusses a recently published trial exploring the simultaneous initiation of SGLT2 inhibitors and finerenone (a nonsteroidal mineralocorticoid receptor antagonist) in persons with chronic kidney disease and type 2 diabetes. Here we go!Finerenone with Empagliflozin in Chronic Kidney Disease and Type 2 Diabetes (0:00 – 9:28).Calling keen trainees! (9:29 - 10:28)Trainees, med students, residents: The Rounds Table and Trial Files are looking for keen individuals to support our efforts.Trial Files is a free monthly newsletter on practice-changing trials, delivered straight to your inbox (https://trialfiles.substack.com/).Reach out to fralickmpf@gmail.com if you are interested in getting involved. Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods

5个月前
628
Episode 125 - Top Papers from the 2025 American Diabetes Association (ADA) Session

Episode 125 - Top Papers from the 2025 American Diabetes Association (ADA) Session

Send us a textWelcome back Rounds Table Listeners! We are back today with a special Rapid Fire Podcast. This week, Dr. Mike Fralick and guest host Danielle Cutler discuss the top papers from the 2025 American Diabetes Association (ADA) Scientific Session. Hot off the presses, here we go!Once-Monthly Maridebart Cafraglutide for the Treatment of Obesity — A Phase 2 Trial (0:00 - 6:05)Orforglipron, an Oral Small-Molecule GLP-1 Receptor Agonist, in Early Type 2 Diabetes (6:06 - 13:22)Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes (13:23 - 20:35)The Good Stuff:Diabetes Trial Files - Free monthly newsletter! Subscribe at https://diabetestrialfiles.substack.com/ (20:36 - 21:00)Congrats to Danielle and all the med students finishing their academic year! (21:01 - 21:57)Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods

6个月前
1317
Episode 124 - 2024 KDIGO Clinical Practice Guidelines for Chronic Kidney Disease

Episode 124 - 2024 KDIGO Clinical Practice Guidelines for Chronic Kidney Disease

Send us a textWelcome back Rounds Table Listeners! Today we have the next episode in our Clinical Practice Guidelines series. Drs. Mike and John Fralick discuss the top takeaways from the 2024 KDIGO Clinical Practice Guidelines for chronic kidney disease. Here we go!1. KDIGO 2024 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease (0:00 - 24:24)Access the KDIGO 2024 "Top 10 Takeaways" PDFs here: https://kdigo.org/guidelines/ckd-evaluation-and-management/The Good Stuff:Nephrology Trial Files - https://nephrotrialfiles.substack.com/ (24:25 - 24:48)The Phoenician Scheme (24:49 - 25:33)Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods

6个月前
1533
Episode 123 - Trial Files Top 5 RCTs

Episode 123 - Trial Files Top 5 RCTs

Send us a textWelcome back Rounds Table Listeners! Today we have another special episode— Trial Files turns two years old this June, and we're celebrating with an episode summarizing the Top 5 RCTs in the Trial Files catalogue to date. Dr. Mike Fralick takes us through five trials in 15 minutes. Here we go!1. Effects of Semaglutide on Chronic Kidney Disease in Patients with Type 2 Diabetes (0:00 - 3:08)2. Restrictive or Liberal Transfusion Strategy in Myocardial Infarction and Anemia (3:09 - 5:37)3. Once-Weekly Semaglutide in Persons with Obesity and Knee Osteoarthritis (5:38 - 8:33)4. Antibiotic Treatment for 7 versus 14 Days in Patients with Bloodstream Infections (8:34 - 11:22)5. Finerenone in Heart Failure with Mildly Reduced or Preserved Ejection Fraction (11:23 - 13:23)Happy 2nd Birthday, Trial Files!A free monthly newsletter on practice-changing trials, delivered straight to your inbox-- sign up at https://trialfiles.substack.com/ (13:24 - 14:19)Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods

6个月前
859
Episode 122 - Opioids vs. Non-Opioids for Chronic Pain, IV Albumin for SBP, and PPI for GI Bleed

Episode 122 - Opioids vs. Non-Opioids for Chronic Pain, IV Albumin for SBP, and PPI for GI Bleed

Send us a textWelcome back Rounds Table Listeners! Today we're introducing a new format—the first episode in our Trial Files series, where we provide an overview of a recent Trial Files issue. This week, Dr. Mike Fralick discusses three trials included in a recent throwback issue: opioids versus non-opioids for chronic pain; IV albumin for renal impairment and mortality; and omeprazole before endoscopy in patients with GI bleed. Three trials, 9 minutes, here we go!1. Effect of Opioid vs Nonopioid Medications on Pain-Related Function in Patients With Chronic Back Pain or Hip or Knee Osteoarthritis Pain: The SPACE Trial (00:00 - 2:46)2. Effect of Intravenous Albumin on Renal Impairment and Mortality in Patients with Cirrhosis and Spontaneous Bacterial Peritonitis (2:47 - 4:50)3. Omeprazole before Endoscopy in Patients with Gastrointestinal Bleeding (4:51 - 7:39)What is Trial Files?A free monthly newsletter on practice-changing trials, delivered straight to your inbox-- sign up here! (7:40 - 8:40)Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods

7个月前
520