Episode 140 - Spironolactone vs. Amiloride for Resistant Hypertension

<p><a target="_blank" href="https://www.buzzsprout.com/twilio/text_messages/1743909/open_sms">Send us a text</a></p><p>Welcome back Rounds Table Listeners! Today we have a solo episode with Dr. Mike Fralick. This week, he discusses a recent trial examining whether amiloride is noninferior to spironolactone in reducing systolic blood pressure in patients with resistant hypertension. Here we go!</p><ol><li><a href='https://jamanetwork.com/journals/jama/article-abstract/2834040'>Spironolactone vs Amiloride for Resistant Hypertension: A Randomized Clinical Trial</a> (0:00 – 8:10).</li></ol><p>Run-in studies:</p><ul><li><a href='https://link.springer.com/article/10.1007/s11606-018-4344-7'>Application and impact of run-in studies</a></li><li><a href='https://link.springer.com/article/10.1007/s11606-018-4349-2'>Application and Impact of Run-In Studies for the Evaluation of Statin Efficacy and Safety</a></li></ul><p>The Good Stuff (8:11 - 9:14):</p><ul><li>Trial Files: <a href='https://trialfi...