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LabMind

作者: ARUP Laboratories

最近更新: 4周前

<p>Join Dr. Jon Genzen, professor of pathology with the Spencer Fox Eccles School of Medicine at the...

Recent Episodes

An Interview With Dr. Brian Jackson: The LabMind Journey

After seven years and almost 100 episodes of LabMind recorded, Dr. Brian Jackson, former medical director at ARUP Laboratories and faculty with the Spencer Fox Eccles School of Medicine at the University of Utah, has moved into a new clinical laboratory leadership position at the University of Maryland—leaving the podcast mic behind for a clinical challenge he always knew he wanted to take in his career. During Dr. Jackson’s final episode, he shares his thoughts on a variety of topics, including the state of U.S. healthcare and the contributions of pathology, while also reflecting on his time hosting this podcast. Related Information:• LabMind - An Interview With Dr. Carl Kjeldsberg (Part I): Founding and the Early Shaping of ARUP https://arup.utah.edu/education/podcasts/labmindEp2.php• LabMind - An Interview With Dr. Carl Kjeldsberg (Part II): Scaling ARUP into a Mature Company https://arup.utah.edu/education/podcasts/labmindEp3.php• LabMind - An Interview With Lab Superheroes: Stories of Ingenuity, Creativity, and Grit (Part II) https://arup.utah.edu/education/podcasts/labmindEp50.php• LabMind - An Interview With Rick Panning: How Laboratories Can Reduce the Total Cost of Care https://arup.utah.edu/education/podcasts/labmindEp36.php

4周前

2345

An Interview With Dr. Shaiba Ansari-Ali: Resilience in Medicine and in Life

In 2016, Dr. Shaiba Ansari-Ali, a rheumatologist with Northwestern Medicine, experienced a near-fatal stroke that was followed by a misdiagnosed case of sepsis. In this interview, she explains how her positivity and tenacity were key to her successful rehabilitation and recovery, and she illustrates how this experience has made her a better physician despite her physical limitations.Related Information:YouTube Series: “Mansplaining Medicine” (https://www.youtube.com/channel/UCkpqin9U2WgT423DqJo2guQwould) Book: “When the Doctor Has a Stroke: (How I recovered, and you can too)” (https://www.amazon.com/dp/B08LNLCLF9/ref=cm_sw_r_cp_ud_dp_G68R6WEVAJEPMFJFY2CP?skipTwisterOG=1)

2个月前

2593

An Interview With Cherise Shockley: How Laboratory Data Can Empower Patients

As laboratory professionals, we’re often focused on our critical role as part of the healthcare team in delivering results to providers. But, do we ever stop and think about the power laboratory data can have in the hands of the patients themselves? In this interview, Cherise Shockley, a diabetes social media advocate, describes her experience being diagnosed with an under-recognized form of diabetes and shares how her continuous glucose monitor (CGM) and laboratory test results have helped her take control of her disease and her life.

4个月前

2340

An Interview With Dr. Benjamin Bradley: The Central Role of Clinical Laboratories in Controlling Emerging Pathogens

Whenever a new infectious disease enters the scene (or reenters, as in the case of measles), developing precise and accurate diagnostic tests as quickly as possible is critical. In this interview, Dr. Ben Bradley, ARUP medical director of the Institute for Research and Innovation in Infectious Disease Genomic Technologies, High Consequence Pathogen Response, Virology, and Molecular Infectious Diseases, describes various challenges in rapidly setting up and maintaining testing capacity for these kinds of diseases and why we need collaboration between academic, clinical, and public health labs.Webinar: Emerging Viral Diseases: A 2025 Update for Laboratorians [https://arup.utah.edu/education/bradley-emergingviral-2025.php]; Measles by Real-Time PCR: A Rapid and Reliable Method for Measles Testing [https://www.youtube.com/watch?v=NZdZDPv-oTw]

5个月前

2453

An Interview With Dr. Ryan Metcalf: The Art and Science of Creating a Clinical Guideline

In this age of algorithms, how do we ensure clinical care is both science based and personalized? In this interview, Dr. Ryan Metcalf, section chief of Transfusion Medicine at ARUP Laboratories and University of Utah Health and associate professor of Pathology at the University of Utah School of Medicine, shares the story behind the new platelet transfusion guideline from the Association for the Advancement of Blood and Biotherapies (AABB). He describes how the authors addressed patient-specific variation and the inherent uncertainty of scientific evidence. Related Information: Platelet Transfusion: 2025 AABB and ICTMG International Clinical Practice Guidelines [https://arup.utah.edu/education/metcalf-platelet-2025.php/]JAMA® Article: Platelet Transfusion: 2025 AABB and ICTMG International Clinical Practice Guidelines [https://jamanetwork.com/journals/jama/fullarticle/2834703]JAMA® Clinical Reviews Podcast: Platelet Transfusion: Best Practice Guidelines [https://edhub.ama-assn.org/jn-learning/audio-player/18977738]

6个月前

2689

An Interview With Dr. Octavia Peck Palmer: Diversity, Equity, and Personalized Medicine

Health equity and personalized medicine share a common goal: tailoring care to the needs of each individual. In this interview, Dr. Octavia Peck Palmer from the University of Pittsburgh Medical Center, immediate past president of ADLM, explains how diversity is foundational to advancing clinical science and improving patient outcomes.

6个月前

2593

An Interview With Dr. David Fajgenbaum: Embracing the “Ignorome” To Expedite Clinical Science

After nearly dying from a mysterious disease during medical school, Dr. David Fajgenbaum dedicated his career to breaking down barriers in biomedical research. Fajgenbaum is now an associate professor of medicine at the University of Pennsylvania and cofounder of Every Cure. In this conversation, we discuss his personal diagnostic journey and the errors and delays he encountered along the way. We also explore why academic medicine needs to go beyond generating disparate pieces of scientific knowledge and instead turn that information into nodes on a network that spans specialty silos to speed the discovery of effective treatments.

7个月前

2440

An Interview With Amanda Openshaw: The Laboratory Is a Mystery Machine of Diagnostics

Every specimen represents a potential mystery, and laboratory professionals often play the role of detectives. For the 2025 Lab Week episode of LabMind, Amanda Openshaw, a genetic counselor at ARUP, shares examples illustrating the importance of good investigative work in the laboratory to discover accurate diagnoses.

9个月前

2829

An Interview With Dr. Qinwen Mao: Why We Need Better Laboratory Tests for Dementia

Why hasn’t there been more progress in developing therapies for Alzheimer’s disease and related forms of dementia? One reason has been the lack of specific laboratory tests that can properly diagnose and characterize these diseases. In this interview, Dr. Qinwen Mao from the University of Utah describes how her research team is helping to bring new blood and cerebrospinal fluid biomarkers into clinical practice to step up the fight against these devastating diseases. Related Information: Webinar: Innovations in Diagnostics for Alzheimer’s Disease and Related Dementias (aruplab.com/AlzInnovations)

10个月前

1543

An Interview With Dr. Keith Elkins: What Doctors Really Want From Their Clinical Laboratories

As laboratory professionals, we may think we have a good understanding of how physicians use our services. But how often do we ask them for practical feedback? In this interview, family physician Dr. Keith Elkins shares his perspectives on what clinical laboratories and pathologists do well, and what opportunities they may be overlooking to better support frontline clinical care.

11个月前

2068

An Interview With Beverly Rauch: Regulating the Safety and Effectiveness of Clinical Laboratory Testing

Many people in the healthcare profession know that clinical laboratories are under more rigorous regulatory scrutiny than just about any other area of medicine. What they may not know is that the New York State Department of Health (NY DOH) was the pioneer in laboratory regulation, starting long before the implementation of either the FDA Medical Device Amendments or the Clinical Laboratory Improvement Amendments (CLIA) of 1988. In this interview, Beverly Rauch, MS, director of the NY DOH’s Clinical Laboratory Evaluation Program (NY CLEP), describes its process for granting permits, inspecting laboratories, and approving assays, and what the new FDA LDT rule might mean for the program.

13个月前

1993

An Interview With Dr. Jenna Rychert: Demystifying Data Analysis for the Clinical Lab

In this age of ChatGPT, artificial intelligence (AI), and machine learning, laboratory professionals might think they need to be experts in sophisticated new technology to glean insights from laboratory data. But as ARUP’s medical director of operational informatics Dr. Jenna Rychert points out in this interview, data analysis doesn’t always have to be complicated to provide meaningful value. Related Information: Laboratory-Developed Tests Account for a Small Minority of Tests Ordered in an Academic Hospital System [hyperlinked to: https://pubmed.ncbi.nlm.nih.gov/37265129/

2024/11/19

1880

An Interview With Dr. Suzanne Dintzis: The Human Side of Pathology’s Digital Transformation

Anatomic pathology is on the verge of its biggest technologic shift in over a century. Making a smooth transition will require leadership to pay as much attention to the human impact as to the technology itself. In this discussion, Dr. Suzanne Dintzis from the University of Washington explains why hospital and department leaders will need to partner with front-line laboratory professionals and pathologists who perform the day-to-day work.

2024/10/14

2505

An Interview With Dr. Jonathan Genzen: Answering Your Questions About the FDA’s Final Rule on LDTs

As of September 2024, there remains enormous uncertainty about the FDA’s final rule on laboratory-developed tests (LDTs). Will it hold up in court? Which tests are subject to which requirements? How can laboratories best prepare? In this interview, Dr. Jonathan Genzen, ARUP’s chief medical officer and senior director of governmental affairs, responds to questions sent in by members of the laboratory community. Related Information: ARUP Resources on the FDA’s Final Rule on Laboratory-Developed Tests (https://www.aruplab.com/fda-ldt-final-rule)ARUP Webinar--The FDA’s Final Rule on LDTs: What You Need To Know (https://youtu.be/nGQ3sRfWkBg)ARUP Files Declaration to Support Lawsuit Challenging the FDA's Rule to Regulate Lab-Developed Tests (https://www.aruplab.com/news/05-30-2024/arup-files-declaration-support-lawsuit-challenging-fdas-rule) FDA email address for questions on the final rule: (ldtfinalrule@fda.hhs.gov)

2024/9/10

2634

An Interview With Dr. Vikas Saini: Creating a More Just, Effective, and Affordable Healthcare System

Fixing American healthcare will require more than mere tweaks around the edges. Dr. Vikas Saini, president of the Boston-based Lown Institute, believes that it will require a return to medicine’s humanist roots. In this interview he describes some of the ways in which many healthcare organizations prioritize revenue and profit over patients and communities. He also explains why he remains optimistic that Hippocratic principles will ultimately prevail. Related Information: Lown Institute (https://lowninstitute.org/)2024 Top Hospitals: America’s Most Socially Responsible Hospitals (https://lownhospitalsindex.org/the-most-socially-responsible-hospitals-in-the-u-s-2024/)2023 Shkreli Awards: The Lown Institute’s Top Ten List of the Worst Examples of Profiteering and Dysfunction in Healthcare (https://lowninstitute.org/projects/2023-shkreli-awards/)

2024/8/13

2396

An Interview With Isak Schmidley: What ASCP's Youngest MLS Can Teach Us About Recruiting the Next Generation of Laboratory Scientists

Clinical laboratories offer great careers, but lack of awareness and other barriers can prevent excellent candidates from pursuing laboratory science professions. In this interview, Isak Schmidley, MLS(ASCP), explains how he first stumbled across medical laboratory science while attending community college in his early teens and then persevered past age stereotypes to land his first hospital laboratory job at the impressive age of 16. He shares advice for laboratory leaders on what his generation expects from employers and tips on how to recruit the next generation.

2024/8/5

1308

An Interview With Dr. Brian Shirts: Preventing Hereditary Cancer Through Genealogy

Most hereditary cancers, including those associated with BRCA1 mutations and Lynch syndrome, can be prevented through a combination of genetic testing, surveillance, and surgery. Yet only a small minority of eligible individuals currently receive this lifesaving intervention. In this interview, Dr. Brian Shirts, director of the Institute for Public Health Genetics at the University of Washington, discusses a new nonprofit organization that uses family connections to identify individuals at high risk for hereditary cancers and other adult-onset hereditary diseases. connectmyvariant.org #connectmyvariant

2024/7/2

2079

An Interview With Dr. Yuan Ji: Bringing Pharmacogenomics Into Mainstream Clinical Practice

Due to genetic variation, patients metabolize and respond to medications in vastly different ways, so why do most drug therapy regimens continue to be one-size-fits-all? In this interview, Dr. Yuan Ji, ARUP’s section chief of Molecular Genetics and Genomics, discusses how currently available genetic tests can be used to improve both the safety and effectiveness of pharmacotherapy. Related Content: Current Clinical Pharmacogenomic Testing: How Do Clinical Laboratories Stay on Top of Changes to Technologies, Professional Guidelines, and Regulations? https://arup.utah.edu/education/ji-pharmtest-2024.php

2024/6/5

2393

An Interview With Dr. Jane Dickerson: Building a Professional Community for Laboratory Stewardship

Since its founding in 2013 at Seattle Children’s Hospital, PLUGS (Patient-Centered Laboratory Utilization Guidance Services) has brought together laboratory professionals, genetic counselors, clinicians, patients, and insurance companies across the country to improve the application of laboratory tests in clinical practice. In this interview, PLUGS cofounder Dr. Jane Dickerson describes some of the ingredients that have contributed to the program’s remarkable success.

2024/5/1

1666

An Interview With Dr. Eddie Stenehjem: What It Means for a Laboratory to Be Part of the Patient Care Team

Dr. Eddie Stenehjem, Vice Chair of Medicine at the University of Colorado, knows a lot about clinical laboratories. As an infectious disease physician and former cochair of Intermountain Healthcare’s laboratory stewardship committee, he has deep respect for the knowledge and dedication that laboratory professionals bring to patient care. In this interview he discusses why clinician-lab collaboration is vital, and how labs can improve communication and relationships with clinical colleagues.

2024/3/21

2534

An Interview With Dr. Joseph Rudolf: How Will Automation Change Clinical Laboratories?

There’s plenty of excitement around laboratory automation. But which tasks are good candidates for automation, and which are poor candidates? What risks need to be managed? And what are the implications of automation for lab professionals? In this interview, Dr. Joseph Rudolf, medical director of ARUP’s Automated Core Laboratory, shares his insights along with some predictions for the future.

2024/2/28

1194

An Interview With Dr. Karen Moser: Solving Coagulation Mysteries One Patient at a Time

Diagnosis involves much more than a number on a lab report. This is particularly true when the patient has disordered bleeding or clotting. In this interview, Dr. Karen Moser from the University of Utah Department of Pathology describes some of the ways she works with her laboratory and clinician colleagues to ensure that patients get the answers and the therapies they need.

2024/1/31

1679

An Interview With Nancy Ross: The Human Side of Quality Management

What does it mean to have a quality culture? Technical competence and strict adherence to protocols are certainly part of the story. But so are factors such as workforce engagement and customer service. In this interview, Nancy Ross, assistant director of clinical pathology and quality at Montefiore Medical System and the founder of Improov, a laboratory improvement consulting company, draws on her diverse career experience to argue for a holistic and people-centered approach to quality management.

2023/12/20

1766

An Interview With Dr. Ryan Metcalf: Why Quality Management Is Critical to the Long-Term Success of Healthcare AI

A public debate is raging around the regulation of artificial intelligence (AI). One side argues that AI is potentially dangerous and needs to be carefully controlled, whereas the other side argues that any regulation would slow innovation. In this interview, Dr. Ryan Metcalf, section chief of Transfusion Medicine and medical director of Transfusion Service/Blood Bank at ARUP Laboratories, makes a strong case for a safety-first approach to healthcare AI. He also explains why embedding AI development and use within a strong quality management framework could actually lead to more innovation over the long term, even as it prevents patient harm in the short term.RELATED INFORMATION: Creation and Adoption of Large Language Models in Medicine

2023/11/30

2181

An Interview With Drs. Meghan Delaney and Eric Konnick: How FDA Restrictions on Laboratory-Developed Tests Will Harm Patients and Increase Costs

The FDA recently announced a plan to regulate laboratory-developed tests (LDTs) as medical devices. In this interview, Dr. Meghan Delaney from Children’s National Hospital and Dr. Eric Konnick from the University of Washington explain why many tests that are critical to patient care, particularly in the areas of pediatrics, transplantation, and rare diseases, may become unavailable if the rule the FDA has proposed is enacted. Other tests may remain available, but at a significantly increased cost. Dr. Jonathan Genzen, ARUP’s chief medical officer and cohost of this episode, describes how laboratory professionals can provide public feedback to the FDA before the rule takes effect.Related Information:Click Here to access the FDA public comment webpage for the newly proposed LDT rule. ARUP Joins Industry Partners in Opposing Proposed FDA Rules Seeking to Regulate Laboratory-Developed Tests ACLA Opposes Unilateral FDA Action to Regulate Laboratory Developed Tests Under Medical Device Authority Laboratory-Developed Tests Account for a Small Minority of Tests Ordered in an Academic Hospital System Laboratory-Developed Tests: A Legislative and Regulatory Review

2023/11/6

2505

An Interview With Dr. Ila Singh: What the TRUU-Lab Initiative Has Taught Us About Laboratory Test Names

Dr. Ila Singh, chief of laboratory medicine at Texas Children’s Hospital, founded the Test Renaming for Understanding and Utilization in the Laboratory (TRUU-Lab) initiative several years ago to tackle challenges related to the nonstandardized and uninformative naming of laboratory tests. In this interview, Dr. Singh describes the surveys her CDC-funded collaborative has conducted with hundreds of physicians and other providers, and she shares insights about how to improve the ordering of tests through more effective naming.Related Information:Click Here to Listen to this Podcast Episode on the ARUP EDU Official Website.Click Here to Listen to Dr. Singh's 2019 Appearance on LabMind Entitled "An Interview with Dr. Ila Singh: The TRUU-Lab Initiative to Improve Laboratory Test Names." Click Here to View Dr. Singh's 2019 Video Lecture Entitled "Ordering the Right Lab Test: It All Begins With the Right Test Name."

2023/10/19

1486

An Interview With Dr. Michael Cohen: Blunt Advice for Navigating a Career in Academic Medicine

Individuals pursue careers in academic medicine for many reasons. A love of organizational politics is rarely one of them, but faculty need to understand potential landmines if they are to avoid them. In this interview, Dr. Michael Cohen, a professor emeritus of pathology at Wake Forest University, draws on his experiences serving on faculty and in senior leadership at multiple institutions to explain how to thrive within the paradoxes of academic medicine.Click here to listen to this episode on ARUP's website.Related Information: VIDEO LECTURE: A Discourse on Working in Academic Health Centers With Some Practical Observations by Michael B. Cohen, MD

2023/8/30

1884

An Interview With Glen Garrick: Sustainability in Healthcare Organizations

Sustainability is a hot topic for American corporations, and health systems are no exception. In this interview, Glen Garrick, system sustainability director for Intermountain Healthcare, explains how his and other healthcare organizations are addressing their environmental, social, and governance responsibilities. He also describes how clinical laboratories can make the most positive impact.Related Information:New Building Embodies ARUP’s Commitment to Environmental StewardshipARUP’s Environmental Sustainability Efforts Pay OffRecycling Coalition of Utah Names ARUP the Thomas A. Martin Business Recycler of the Year Impressive New Structure Will Enhance ARUP’s Environmental Stewardship Efforts Top 10 Ways ARUP Helps Our Environment Click Here to Listen to This Episode from the ARUP Website

2023/8/17

2256

An Interview With Dr. Marc Couturier: Keys to Laboratory Success in the Next Pandemic

Three and a half years after the emergence of COVID-19 is a good time to reflect on the capabilities of U.S. laboratories to respond to future pandemics. In this interview, Dr. Marc Couturier, medical director of Emerging Public Health Crises at ARUP Laboratories, explains how the U.S. laboratory sector has improved in its ability to respond quickly to emerging and reemerging infections, but he emphasizes the need to go further. He specifically explains why testing can’t be rapidly scaled up unless there’s tight coordination between public health labs and clinical labs (particularly reference labs and large academic labs).Click here to Register for Dr. Marc Couturier's Upcoming Webinar entitled: “How to Avoid Building an Airplane Mid Flight: Lab Medicine in the Face of Emerging Public Health Crises” Click Here to Listen to this Episode on ARUP's Official Website.

2023/8/1

2401

An Interview With Clint Child: Bridging the Cultural Divide Between Nursing and Laboratory Medicine

Nurses and laboratory professionals rely on each other to ensure accurate test results, but their relationships are sometimes challenging. As president of St. Alphonsus Medical Center in Nampa, Idaho, as well as a registered nurse with a doctorate degree in nursing practice, Clint Child often mediates when these two professional cultures collide. In this interview, he explains why nursing practice is less predictable and requires greater flexibility than laboratory practice. He also shares his perspective on why it’s valuable for hospital leaders to have strong ties to their local communities. Click Here to view this episode of the LabMind podcast on ARUP's website.

2023/7/11

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