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<p>TWiM describes Shigella infection is facilitated by interaction of human enteric α-defensin 5 with a colonic epithelial receptor, and an amino acid change in RNA polymerase that leads to resistance to β-lactams by preventing dysregulation of amino acid and nucleotide metabolism</p> <p>Hosts: <a href= "https://en.wikipedia.org/wiki/Vincent_Racaniello" target="_blank" rel="noopener">Vincent Racaniello</a>, <a href= "http://academicdepartments.musc.edu/immunology/Faculty/schmidt.html" target="_blank" rel="noopener">Michael Schmidt</a>, <a href= "https://biology.wustl.edu/people/petra-levin" target="_blank" rel= "noopener">Petra Levin</a> and <a href= "https://medschool.umich.edu/profile/2682/michele-s-swanson" target="_blank" rel="noopener">Michele Swanson</a>.</p> <p>Subscribe to TWiM (free) on <a href= "http://itunes.apple.com/us/podcast/this-week-in-microbiology/id422332846&ls=1https://itunes.apple.com/us/podcast/this-week-in-microbiology/id422332846?mt=2&ls=1" target="_blank" rel="...