Understanding Preload Deficiency in SLE: A New Look at Fatigue and Exercise Intolerance

Host: Ryan Quigley <br> Guest: Luigi Adamo, MD, PhD <br> Guest: Andrea Fava, MD <br> <article data-scroll-anchor="true" data-testid="conversation-turn-4" data-turn="assistant" data-turn-id="request-WEB:7e8fa595-d3d5-4c8b-8ec6-b553518bb4be-1" dir="auto" tabindex="-1"> <div> <div tabindex="-1"> <div> <div data-message-author-role="assistant" data-message-id="89675e42-1d0d-40ff-b9db-9afddd2181b5" data-message-model-slug="gpt-4o" dir="auto"> <div> <div> <p data-end="681" data-is-last-node="" data-is-only-node="" data-start="102">Fatigue and exercise intolerance in patients with systemic lupus erythematosus (SLE) may persist even when disease activity is controlled, and preload deficiency could be an overlooked cause. In this expert-led discussion, Drs. Luigi Adamo and Andrea Fava share insights from their research, highlighting diagnostic clues, the role of NT-proBNP, and emerging interventions aimed at improving quality of life. Dr. Adamo is an Associate Professor of Me...