Unraveling the APOE 4 Gene and the Alzheimer's Puzzle

<p>This episode is part of a live recording for our NEURO Academy community, and the topic of the discussion is the genetics of Alzheimer's disease, in particular a deep dive into Apolipoprotein E4 or APOE4 gene, which is the most influential genetic risk factor associated with Late Onset Alzheimers Disease.<span class= "Apple-converted-space"> </span> We describe the evolutionary aspects of Apolipoproteins, how they are produced, how the different isoforms of apoe influence the different factors leading to AD, how it effects lipid metabolism and immune functions in the brain, and what is the latest evidence on the epigenetic of APOE4. Typically, the community members post their questions ahead of time and we structure the conversation in a way to address their questions, and also answer their questions during the recording.<span class="Apple-converted-space"> </span></p> <p> </p> <p>NEURO Academy is a membership based online community with over 700 active members, with resources to ac...