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<p>Psilocybin — the psychedelic compound in so-called “magic mushrooms” — has exploded into headlines and social media feeds. Some call it a miracle cure for depression, others dismiss it as hype. In this episode, I take a clear-eyed look at what the science really says.</p><p>I’ll start with Sarah’s story — a young scientist whose life was turned upside down by a cycling accident and who found hope again through a psilocybin clinical trial at Johns Hopkins. Her words: <em>“This trial changed my life.”</em></p><p>From there, I explore:</p><ul><li>The history of psilocybin, from ancient rituals to 1960s psychiatry to today’s “psychedelic renaissance.”</li><li>The <strong>online buzz</strong>, where psilocybin is hyped as everything from a creativity booster to a trauma cure.</li><li>The <strong>scientific evidence</strong>, from small pilot trials to the largest modern RCTs.</li><li>The <strong>neuroscience</strong>, showing how psilocybin may “reset” rigid brain networks, boost plastic...