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<p>On October 2, 2025 Dan Lodge returned to the podcast to talk about the physiological changes in brain circuits associated with schizophrenia. We reviewed the status of the dopamine hypothesis of schizophrenia and the brain circuits responsible for its negative, positive, and cognitive symptoms.</p><p>Guest: </p><p>Dan Lodge, Professor and Chair, Department of Pharmacology, Long School of Medicine, UT San Antonio</p><p>Participating:</p><p>Matt Wanat, Department of Neuroscience, Developmental and Regenerative Biology, UT San Antonio</p><p>Host:</p><p>Charles Wilson, Department of Neuroscience, Developmental and Regenerative Biology, UT San Antonio</p><p>Thanks to Jim Tepper for original music</p>