EP 201: The gene therapy playbook: Successes, setbacks, and the path forward with Richard Wilson of Astellas

<p>This week on The Genetics Podcast, Patrick is joined by Richard Wilson, Senior Vice President, Primary Focus Lead of Genetic Regulation at Astellas. They discuss where the gene therapy field stands today, diving into successes, persistent barriers, regulatory considerations, manufacturing strategies, and other reflections on important approaches to precision medicine drug development.</p><p><strong>Show Notes: </strong></p><p><strong>0:00 </strong>Intro to The Genetics Podcast</p><p><strong>00:59</strong> Welcome to Richard</p><p><strong>01:33 </strong>Current wins and challenges in gene therapy </p><p><strong>07:13 </strong>The need for more open non-competitive data sharing and a clearer pathway towards reimbursement and incentivization</p><p><strong>11:15 </strong>Building post-approval systems into the genomic medicine lifecycle</p><p><strong>14:47 </strong>Rethinking evidence standards in rare disease trials, and the global push for regulatory and reimbursement alignment</p><p>...