EP 190: Targeting regeneration to tackle Duchenne Muscular Dystrophy with Frank Gleeson of Satellos

<p><strong>Summary: </strong></p><p>This week on The Genetics Podcast, Patrick is joined by Frank Gleeson, co-founder and CEO of Satellos. They discuss Satellos’ novel approach to treating Duchenne Muscular Dystrophy by targeting muscle stem cell regeneration, how this fills a critical therapeutic gap, and the promising results of their early clinical trials. They also touch on what it takes to advance drug development and secure funding in today’s biotech landscape.</p><p><strong>Show Notes: </strong></p><p><strong>0:00 </strong>Intro to The Genetics Podcast</p><p><strong>01:00</strong> Welcome to Frank and the origin story for Satellos and its focus on muscle stem cell regeneration to treat Duchenne Muscular Dystrophy (DMD)</p><p><strong>14:03</strong> Counteracting degeneration in DMD and associated mechanisms</p><p><strong>16:08 </strong>Current therapeutic focuses in DMD, including gene therapy and exon skipping to increase expression of dystrophin</p><p><strong>24:28</strong> Sat...