EP 216: Four decades of advancing Duchenne research with Jeffrey Chamberlain of University of Washington

EP 216: Four decades of advancing Duchenne research with Jeffrey Chamberlain of University of Washington

Published on Dec 4
47分钟
The Genetics Podcast
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<p><strong> </strong>This week on The Genetics Podcast, Patrick is joined by Dr. Jeffrey Chamberlain, Professor at the University of Washington School of Medicine, co-founder of Kinea Bio, and Director of the Muscular Dystrophy Cooperative Research Center of Seattle. They discuss the early breakthroughs that revealed the structure and function of the dystrophin gene, how those insights led to the creation of micro-dystrophin and systemic AAV delivery in Duchenne, and the major scientific and clinical challenges the field must now solve.</p><p><strong>Show Notes: </strong></p><p><strong>0:00 </strong>Intro to The Genetics Podcast</p><p><strong>00:59</strong> Welcome to Jeffrey</p><p><strong>01:33</strong> Early discovery of the dystrophin gene and how it shaped Duchenne muscular dystrophy (DMD) research</p><p><strong>09:07 </strong>Efforts to map dystrophin and develop practical diagnostic techniques</p><p><strong>12:04 </strong>How research in Jeffrey’s lab gradually led to the creatio...