Asenapine Pharmacology

<p>Asenapine is an atypical antipsychotic that acts as an antagonist at multiple receptors, including dopamine D2 and serotonin 5-HT2A, contributing to its antipsychotic and mood-stabilizing effects.</p> <p>Adverse effects of asenapine include somnolence, dizziness, and extrapyramidal symptoms.</p> <p>Because asenapine is significantly metabolized by CYP1A2, inhibitors or inducers of these enzymes can affect its plasma concentrations.</p> <p>Co-administration with other CNS depressants may increase the risk of sedation and impaired cognitive or motor function.</p> <p>Asenapine can prolong the QT interval, so caution is advised when used with other medications that affect cardiac conduction.</p> <p class="has-vivid-red-color has-text-color">Be sure to check out our free Top 200 study guide &#8211; <a href="https://www.reallifepharmacology.com/100-free-pharmacology-test/">a 31 page PDF that is yours for FREE!</a></p> <h2 class="wp-block-heading">Support The Podcast and Check Out These Am...