Lifesaving Work No One’s Talking About with Dr. David Fajgenbaum

<p>There’s this phrase Penn and I say a lot when we’re overwhelmed making goofy internet videos—“It’s okay, we’re not saving lives.” But this week, we talk to a man who actually is saving lives and he needs us to help spread the word. <a href="https://time.com/collections/time100-health-2025/7279645/david-fajgenbaum/" rel="noopener noreferrer" target="_blank">Dr. David Fajgenbaum</a> is the founder of <a href="https://everycure.org/" rel="noopener noreferrer" target="_blank">Every Cure</a>, a nonprofit that’s on a mission to do something that sounds impossible—use already-approved drugs to treat diseases they weren’t originally made for. Diagnosed with Castleman disease, Dr. David refused to accept that there was no cure. So, he saved his own life by repurposing existing medication and now he's on a mission to do the same for others.</p><br><p>Using AI to search 75 million possible drug-disease combinations, they’re finding things to help with cancer and autism. They are all in clinica...